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Single-Molecule. Innovation.
High-throughput measurement.
Capture hundreds of DNA-protein interactions in parallel with high-throughput DNA curtains
assays. Designed to maximize statistical
power without sacrificing resolution.
Low-volume microfluidics.
User-friendly microfluidic system that is made for microliter samples at nanomolar concentrations.
Built for repeatable DNA curtains experiments
with minimal setup time.
Fits existing
TIRF microscopes.
Seamless integration with standard fluorescence microscopes - no specialized instrumentation required. Upgrade your system without a new
workflow.
DNA Curtains Flow Cell

We developed a user-friendly, reusable DNA curtains flow cell that integrates smoothly with commercially available fluorescence microscopes. It  features  nanofabricated structures that enable the formation of DNA curtains, supporting high-quality single-molecule experiments.
Its microfluidic design is optimized for microliter-scale samples at nanomolar concentrations, conserving valuable reagents.
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Product
By combining DNA curtains technology with a microfluidic, camera-based readout platform,
the DNA Curtains Flow Cell enables direct visualization of DNA–protein interactions
in parallel rather than sequential measurements. Experiments that traditionally require one-by-one acquisition can now be performed at scale, enabling rapid data collection, improved statistical power, and access to molecular heterogeneity.

The microfluidic design is optimized for microliter-scale samples at nanomolar concentrations, reducing reagent consumption while maintaining experimental performance.
40
Minutes experiment time
100+
DNA molecules per field of view
6
Microfluidic channels
0.5
μL Channel volume
Testimonials
The technique developed by 1NA, combined with fluorescence microscopy, provides high-throughput data of proteins interacting with DNA. Our group is focusing on mitochondrial dysfunctions, where this technique will be our tool of choice for screening drugs targeting the mitochondrial replication machinery.
Prof. Géraldine Farge
at Université Clermont Auvergne
The technique developed by 1NA, combined with fluorescence microscopy, provides high-throughput data of proteins interacting with DNA. Our group is focusing on mitochondrial dysfunctions, where this technique will be our tool of choice for screening drugs targeting the mitochondrial replication machinery.
Prof. Géraldine Farge
at Université Clermont Auvergne
The technique developed by 1NA, combined with fluorescence microscopy, provides high-throughput data of proteins interacting with DNA. Our group is focusing on mitochondrial dysfunctions, where this technique will be our tool of choice for screening drugs targeting the mitochondrial replication machinery.
Prof. Géraldine Farge
at Université Clermont Auvergne
The technique developed by 1NA, combined with fluorescence microscopy, provides high-throughput data of proteins interacting with DNA. Our group is focusing on mitochondrial dysfunctions, where this technique will be our tool of choice for screening drugs targeting the mitochondrial replication machinery.
Prof. Géraldine Farge
at Université Clermont Auvergne
The technique developed by 1NA, combined with fluorescence microscopy, provides high-throughput data of proteins interacting with DNA. Our group is focusing on mitochondrial dysfunctions, where this technique will be our tool of choice for screening drugs targeting the mitochondrial replication machinery.
Prof. Géraldine Farge
at Université Clermont Auvergne
Go single-molecule. Let’s talk about your application.
Let’s discuss
Schedule discussion
To learn more about our product or provide early-stage input, please don't hesitate to schedule a discussion with us.
Book a Call
Address
Galileiweg 8, 2333 BD,

Leiden, The Netherlands
Contact
hello@1na.nl

+31 (0) 681835707
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